- Influence of melting and rheological properties of fatty binders on the melt granulation process in a high shear mixer.
B. Evrard, K. Amighi, D. Beten, L. Delattre and A. Moës
Drug Development and Industrial Pharmacy, 25(11), 1177-1184, 1999
- Comparison of the IV pharmacokinetic in sheep of miconazole – cyclodextrin solution and a micellar solution.
G. Piel, B. Evrard, T. Van Hees and L. Delattre
Int. J. Pharm., 180, 41-45, 1999
- Development of a parenteral and an oral formulation of albendazole with cyclodextrins
G. Piel, B. Evrard, T. Van Hees, G. Llabres and L. Delattre.
STP Pharma Sciences, 9(3) 257-260, 1999
T. Van Hees, G. Piel, B. Evrard, X. Otte, L. Thunus and L. Delattre
Pharm. Res, 16, 12, 1865-1871, 1999
-
Application of supercritical carbon dioxide for the
preparation of a piroxicam-b-cyclodextrin
inclusion compound
T. Van Hees, G. Piel, B. Evrard, X. Otte, L. Thunus and L.
Delattre.
Pharm. Res, 16, 12, 1865-1871, 1999.
- Determination of albendazole and its main metabolites in ovine plasma by liquid chromatography with dialysis as an integrated sample preparation technique
P. Chiap, B. Evrard, M.A. Bimazubute, P. de Tullio, P. Hubert, L. Delattre, J. Crommenn
J Chrom. A, 870, 121-134, 2000
- Molecular Modeling Study of -CD complexes with Miconazole
G. Piel, G. Dive, B. Evrard, T. Van Hees and L. Delattre
Eur.J. Pharm. Sci., 13 (3), 271-279, 2001
- In vitro comparison of the antimycotic activity of a miconazole HP--CD solution to a miconazole surfactant solution
G. Piel, M.P. Hayette, B. Evrard, T. Van Hees, P. Demol and L. Delattre
J. Antimicr. Chem, 48, 83-87, 2001
- A nuclear magnetic resonance study of the miconazole--cyclodextrin inclusion complex in an acidic medium : determination of the structure and stability constants.
G. Piel, G. Llabres, B. Evrard, T. Van Hees, S. Henry de Hassonville and L. Delattre
STP Pharma Sciences 11 (3), 235-238, 2001
- Preparation of mebendazole HP--cyclodextrin complexes using water-soluble polymers and organic acids.
C. Alvarez, T. Van Hees, G. Piel, J-F Liégeois , L. Delattre and B. Evrard
STP Pharma Sciences. 11(12), 129-135, 2001
- IgE-mediated anaphylaxis after first intravenous
infusion of cyclosporine.
D. Ebo, G. Piel, V. Conraads, W. Stevens
Annals Allergy Asthma and Immunology, 87, 243-245, 2001.
- Development and validation of a new Fourier transform infrared spectrometric method for the quantification of urea in creams and ointments
X Otte, B. Evrard, L. Delattre, L. Thunus
Anal. Chim. Acta, 451, 323-328, 2002
- Determination of the free/included piroxicam ratio in cyclodextrin complexes : comparison between UV-spectrophotometry and differential scanning calorimetry.
T. Van Hees, G.Piel, S. Henry de Hassonville, B. Evrard and L. Delattre
Eur. J. Pharm. Sci. 15 (4), 347-353, 2002.
- Albendazole oral bioavailability comparison of a suspension and a solution containing hydroxypropyl--- cyclodextrin.
B. Evrard, P. Chiap, P. De Tullio, F. Ghalmi, G. Piel, T. Van Hees, J. Crommen, B. Losson
and L. Delattre
J. Control. Rel., 85 (1-3), 45-50, 2002
- Application of supercritical carbon dioxide for the preparation of drug/cyclodextrin
inclusion compounds.
T. Van Hees, V. Barillaro, G. Piel, S. Henry de Hassonville,
B. Evrard and L. Delattre
J. Incl. Phenom. Macro., 44 (1-4):271-274, 2002
- Inclusion complexes of cyproterone acetate with cyclodextrins in aqueous solution.
S. Henry de Hassonville, B. Perly, G. Piel, T. Van Hees, L.
Delattre and B. Evrard
J. Incl. Phenom. Macro., 44 (1-4) : 289-292, 2002
- Systematic characterization of oil-in-water emulsions for formulation design
I.Roland, G. Piel, L. Delattre and B. Evrard
Int. J. Pharm, 263 (1-2), 85-94, 2003
- Matériaux pulvérulents et granulaires utilises dans la fabrication des comprimés pharmaceutiques
L. Delattre
Bulletin de la Société Royale Des Sciences de Liège, 72 (5), 317-339, 2003
- Preparation and In Vivo Toxicity Study of Solid Lipid Microparticles as Carrier for Pulmonary Administration
V. Sanna, N. Kirschvink, P Gustin, E. Gavini, I. Roland, L. Delattre, B. Evrard
AAPS PharmaSciTech, 5 (2), article 27, 2003
-
Pathogenic role of matrix metalloproteases and their inhibitors in
asthma and chronic obstructive pulmonary disease and their therapeutic
relevance of matrix metalloproteases inhibitors
D. Cataldo, M. Gueders, N. Sounni, B. Evrard, P. Bartsch, R.
Louis, A. Noel, J.M. Foidart
Cell. And Mol. Biology, 49 (6), 875-884, 2003.
- Skin compatibility of cyclodextrins and their derivatives, a comparative assessment using corneoxenometry
G. Piel, S. Moutard, E. Uhoda, F.Pilard, G.E. Pierard, B. Perly, L. Delattre and B. Evrard
Eur. J. Pharm. Biopharm., 57 (3), 479-482, 2004
- Comparison of two methods currently used to determine the interaction between cyclodextrins and drugs : Phase solubility diagram and NMR spectroscopy.
G. Piel, S. Moutard, B. Perly, S. Henry de Hassonville, P. Bertholet, V. Barillaro, M.Piette, L. Delattre and B. Evrard
J. Drug Deliv Sci. Tech., 14 (1), 91-97, (2004).
- Application of molecular modeling to the study of cyproterone acetate stability in the presence of cyclodextrin derivatives
S. Henry de Hassonville, G. Dive, B. Evrard, V. Barillaro, P. Bertholet, L. Delattre and G. Piel
J. Drug Deliv. Sc. Tech., 14 (5), 357-362, 2004
- Modulation of the arachidonic cascade with 3 fatty acids or analogues: potential therapeutic benefits,
I. Roland, X. de Leval, B. Evrard, B. Pirotte, J-M Dogné and L. Delattre
Mini Rev Med Chem., 4 (6), 659-668, 2004
- Cyclodextrins as a potential carrier in drug nebulization.
B Evrard, P Bertholet, M Gueders, M-P Flament , G Piel, L. Delattre,A Gayot, P Leterme, JM Foidart and D Cataldo
J. Control. Rel., 96, (3), 403-410, 2004
- Development and validation of a high-performance liquid chromatographic method for the determination of cyproterone acetate in human skin,
S. Henry de Hassonville, P. Chiap, J.-F. Liégeois, B. Evrard, L. Delattre, G. Piel and P. Hubert
J. Pharm Biomed Anal., 36 (1), 133-143, 2004
- Delivery of granulocyte-Macrophage colony-stimulating factor in bioadhesive hydrogel stimulates migration of dendritic cells in model of human papillomavirus-associated (pre)neoplastic epithelial lesions
P. Hubert, B. Evrard, C. Maillard, E. Franzen-Detrooz, L. Delattre, J.M. Foidart, A. Noel, J. Boniver and P. Delvenne
Antimircob. Agents Chemotherp., 48 (11), 4342-4348, 2004
- Effect of acidic ternary compounds on the formation of miconazole/cyclodextrin inclusion complexes by means of supercritical carbon dioxide,
V. Barillaro, P. Bertholet, H. Henry de Hassonville, E. Ziémons, B. Evrard, L. Delattre and G. Piel
J. Pharm. Pharm. Sci., 7 (3), 378-388, 2004
-
Oral bioavailability in pigs of a miconazole/hydroxypropyl-ß-cyclodextrin/L-tartaric
acid inclusion complex produced by supercritical carbon dioxide
processing,
V. Barillaro, B. Evrard, L. Delattre, G. Piel,
The
AAPS Journal, 7(1), 149-1552005. -
Cyclodextrin-mediated drug release from liposomes
dispersed within a bioahesive gel, G. Piel,
L. Boulmedarat, A. Bochot, S. Lesieur, E. Fattal
, Pharmaceutical Research, 22, 962-971,
2005.
-
Automated method for the determination of a
new MMP inhibitor in ovine plasma and serum by coupling of
restricted access material for on-line sample clean-up to liquid
chromatography, P. Chiap, M. Piette, B. Evrard, F.
Frankenne, B. Christiaens, G. Piel, D. Cataldo, JM Foidart, L.
Delattre, J. Crommen, P. Hubert, J. Chrom. B, 817,
109-117, 2005. -
The effect of cyclodextrins on the aqueous solubility
of a new MMP inhibitor: phase solubility, 1H-NMR spectroscopy and
molecular modeling studies, preparation and stability study of
nebulizable solutions, P. Bertholet, M. Gueders, G. Dive, A.
Albert, V. Barillaro, B. Perly, D. Cataldo, G. Piel, L. Delattre, B.
Evrard, Journal of Pharmacy and Pharmaceutical Sciences, F.I.:
1,0670, F. Jamali, Alberta, Canada, 8(2), 164-175, 2005. -
Solid Lipid Microparticles (SLMs): formulation,
preparation, characterisation, drug release and applications, S. Jaspart, G. Piel, L. Delattre, B.
Evrard , Expert Opinion on Drug Delivery, 2, 75-87, 2005. -
Betamethasone-in-cyclodextrin-in-liposome: the effect of
cyclodextrins on encapsulation efficiency and release kinetics,
Piel Géraldine, Piette Marie, Barillaro Valery,
Castagne Delphine, Evrard Brigitte
and Delattre Luc, International
Journal of Pharmaceutics, 312, 1-2, 75-82, 2006.
-
Inhaled fluticasone reduces bronchial
responsiveness and airway inflammation in cats with mild chronic
bronchitis, Kirschvink Nathalie, Leemans Jérôme,
Delvaux François, Snaps Frédéric, Jaspart Séverine,
Evrard Brigitte, Delattre Luc, Cambier
Carole, Clercx Cécile and Gustin Pascal,
Journal of Feline Medicine & Surgery, 8, 1, 45-54, 2006. -
Pharmacokinetic study of a new synthetic MMP
inhibitor (Ro 28-2653) after IV and oral administration of
cyclodextrin solutions, Piette Marie,
Evrard Brigitte, Frankenne Francis, Chiap
Patrice, Bertholet Pascal, CastagneDelphine, Foidart Jean
Michel, Delattre Luc, Piel Géraldine,
European Journal of Pharmaceutical Sciences,
28, 189-195, 2006.
-
Comparison of FT-NIR transmission and UV–vis spectrophotometry
to follow the mixing kinetics and to assay low-dose tablets
containing riboflavin, C. Bodson, W. Dewé,
Ph. Hubert and L. Delattre,
Journal of Pharmaceutical and Biomedical
Analysis, 41, 3, 783-790, 2006. -
Solid lipid microparticles as sustained
release system for pulmonary drug delivery, S. Jaspart,
P. Bertholet, G. Piel, J.M. Dogné, L. Delattre, B. Evrard,
European Journal of Pharmaceutics and Biopharmaceutics,
65, 1 , 47-56,
2007. -
Solid lipid microparticles as carrier for the
sunscreen agent, octyl-dimethylaminobenzoate, R. Tursilli,
G. Piel, L. Delattre, S. Scalia, European Journal of
Pharmaceutics and Biopharmaceutics, Volume 66, Issue 3, Pages
483-487, 2007. -
Theoretical and experimental investigations
on miconazole/cyclodextrin/acid complexes: molecular modeling
studies, V. Barillaro, G. Dive, P. Bertholet, B.
Evrard, L. Delattre, E. Ziemons, G. Piel, International
Journal of Pharmaceutics, Volume 342, Issues 1-2, Pages 152-160,
2007.
-
Study of the interaction between
cyclodextrins and liposome membranes: effects on the
permeability of liposomes, Piel Géraldine, Piette
Marie, Barillaro Valery,
Castagne Delphine, Evrard Brigitte and Delattre Luc,
International Journal of
Pharmaceutics, Volume 338, Issues 1-2, Pages 35-42, 2007.
-
Study of the relationship between lipid
binding properties of cyclodextrins and their effect on the
integrity of liposomes , G. Piel, M. Piette, V.
Barillaro, D. Castagne, B. Evrard and L. Delattre,
International Journal of Pharmaceutics, Volume 338, Issues
1-2, 29, Pages 35-42, 2007.
-
Validation of manufacturing process of
Diltiazem HCl tablets by NIR spectrophotometry (NIRS), C.
Bodson, E. Rozet, E. Ziemons, B. Evrard, Ph. Hubert and L.
Delattre, Journal of Pharmaceutical and Biomedical
Analysis, Volume 45, Issue 2, Pages 356-361, 2007.
- Effect of cyclodextrins on the viability of
endothelial cells, D. Castagne, L. Belhadj Salem, L. Delattre,
B. Nusgens and G. Piel, Journal of Inclusion Phenomena and
Macrocyclic Chemistry, Volume 57, Issues 1-4, Pages 105-107,
2007.
- Preparation and evaluation of liposomes encapsulating
synthetic MMP inhibitor (Ro 28-2653)-cyclodextrin complexes, M.
Piette, D. Castagne, L.Delattre, G .Piel, Journal of
Inclusion Phenomena and Macrocyclic Chemistry, Volume 57, Issues 1-4,
Pages 101-103, 2007.
- Contribution of cyclodextrins in the development of
different pharmaceutical formulation of a new matrix metalloproteinase
inhibitor, B. Evrard, P. Bertholet,
M. Gueders, M. Piette, G. Piel, D. Cataldo, L. Delattre,
Journal of Inclusion Phenomena and Macrocyclic Chemistry, Volume 57,
Issues 1-4, Pages 303-308, 2007.
- Theoretical and experimental investigations of
organic acids/cyclodextrin complexes and their consequences
upon the formation of miconazole/cyclodextrin/acid ternary
inclusion complexes, V. Barillaro, G. Dive, P.
Bertholet, B. Evrard, L. Delattre, M. Frederich, E.Ziémons, G.
Piel, International Journal of Pharmaceutics, In Press,
Accepted Manuscript.
- Theoretical and experimental vibrational
study of miconazole and its dimers with organic acids:
Application to the IR characterization of its inclusion
complexes with cyclodextrins, Valéry Barillaro,
Georges Dive, Eric Ziémons, Pascal Bertholet, Brigitte Evrard,
Luc Delattre and Geraldine Piel, International Journal of
Pharmaceutics, In Press, Accepted Manuscript.
Articles soumis
-
Automated method for the determination of a new MMP inhibitor in ovine plasma ands serum by coupling of restricted access material for on-line sample clean-up to liquid chromatography
P. Chiap, M. piette, B. Evrard, F. Frankenne, B. Christiaens, G. Piel, D. Cataldo, J. M. Foidart, L. Delattre, J. Crommen, P. Hubert
J. Chrom. B, 2005, in press -
Solid Lipid Micropartcles (SLMs): formulation, preparation, characterisation, drug release and applications
S. Jaspart, G. Piel, L. Delattre, B. Evrard
Expert Opinion a-on Drug Delivery, 2005, in press -
Oral bioavailability in pigs of a miconazole/hydroxypropyl-γ-cyclodextrin/L-tartaric complex produced by supercritical carbon dioxide processing
V. Barillaro, B. Evrard, L. Delattre, G. Piel
The AAPS Journal, 2005, soumis
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